Tablet Dissolution Tester

Tablet Dissolution Tester

Dissolution testing is a key tool for assessing the bioequivalence of pharmaceuticals. It helps predict the rate and extent of drug absorption by simulating the dissolution and release process of the drug in the body. This is essential to ensure that generic drugs have the same efficacy and safety as the originator drugs.
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Products Description

Dissolution test results can help pharmaceutical companies to optimise the dosage form design of a drug, such as choosing the right excipients and formulation process to ensure that the drug is released at the right rate in the body,In the field of pharmaceutical production and quality control, disintegrometer is a precision instrument, which is mainly used to detect the disintegration speed and disintegration of tablets, capsules and other solid preparations under the specified conditions. The use of disintegrator is of vital importance to ensure the quality of medicines and guarantee the safety of medication.

Features

Automation and intelligent control: The disintegrator adopts computer control technology with microcontroller as the core, and intelligently controls the water bath temperature, working time, lifting frequency and other performance parameters.

Precise temperature control: The disintegrator can automatically control the temperature of the water bath, which is usually set at 37.0℃ (Pharmacopoeia regulations), and the preset temperature can be reset at any time. The temperature control accuracy reaches ±0.5℃.

Independent basket system: The disintegrator is usually equipped with several sets of baskets, which can independently carry out disintegration experiments, such as the 4-basket working position system to determine the disintegration time limit.

Electronic Temperature Sensor: An electronic temperature sensor is provided to display and monitor the temperature at various points in the water bath and in the beaker to ensure the accuracy of the experiment.

Automatic lifting basket: The lifting frequency of the basket of the disintegrator is (30-31)/minute, and the lifting distance is (55±1)mm, which ensures that the samples are uniformly heated and stirred in the water bath.

Overheating alarm and automatic protection function: the instrument has a monitoring water bath temperature overheating alarm and automatic protection function to prevent the sample from being damaged by the high temperature.

Preset and Timing Function: The disintegrator allows the user to preset the timing range from 1 minute to 999 minutes with a time control accuracy of ±0.5 minutes.

Sieve design: The minimum distance from the sieve to the bottom of the cup is 25mm ± 2mm, and the aperture of the sieve is 2mm as standard, or 0.425mm or 1mm aperture can be selected.

disintegration apparatus for tablets

Parameter

Name

Disintegration tester

The number of lifting baskets

2

Number of glass tubes in hanging basket

12

Volume of flat-bottomed beaker

1000ml

Basket shuttle frequency

(30~32) times/minute

Basket round trip travel

(55±1) mm

Minimum screen spacing

(25±2) mm

Timing range

(1~900) points

Timing accuracy

±0.5min

Temperature preset range

(20~45)ºC

Automatic temperature control accuracy

±0.5°C

Heater power

500W

Continuous working time

More than 24 hours

Power supply

220V/50Hz

Power

600W

Dimensions

(40*30*42)cm

application

disintegration and dissolution test

disintegration apparatus for tablets 2

Disintegration equipment is used to test the disintegration speed and disintegration of tablets, capsules and other solid preparations under specified conditions, and is an important tool for pharmaceutical research and development, production process control and quality inspection.
 

 

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