Plant Cell Bioreactor
Plant Cell Bioreactor

Plant Cell Bioreactor

Plant Cell Bioreactor is a kind of equipment used for large-scale cultivation of plant cells, which is mainly used for the production of some rare drug resources and plant useful chemical components.
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Anyang Gaokang Medical Co., Ltd. is one of the most reliable manufacturers and suppliers of plant cell bioreactor in China. With a professional production team, we are able to meet the needs of the majority of our customers. Please rest assured to buy premium plant cell bioreactor at competitive price from our factory.

 

Products Description

 

We design bioreactors for plant cell cultures that demand pharmaceutical-grade control. Our Plant Cell Bioreactor from ​​5L to 200KL​​ provide the precise environment needed to maximize yields of paclitaxel, ginsenosides, and other high-value plant-derived compounds.

Technical Superiority for Plant Cell Cultivation​​

✔ ​​Patented Aspect Ratio (1:2.2-2.5)​​ – Optimized oxygen transfer for dense suspensions
✔ ​​Swiss Sensor Integration​​ – Hamilton/Mettler probes for ±0.1 pH and ±3% DO precision
✔ ​​Dual Sterilization Protocols​​ – SIP (121°C/30min) + CIP (360° spray coverage)
✔ ​​Magnetic & Mechanical Drive Options​​ – 50-1000RPM with shear-sensitive paddle designs

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Product Specification

 

Total volume

5L, 10L, 15L, 20L, 30L, 50L, 100L, 200L, 500L, 1000L, 5KL, 50KL, 200KL etc.

Working volume

30%~70%

Tank

Jacket tank, made by SS316 and SS304, tank design pressure 0.3Mpa, jacket design pressure 0.35Mpa, polishing 0.4-0.6um, ratio of diameter and height is 1:2.2-2.5

Stirring system

Mechanical drive on the top/bottom or Magnetic drive on the top, 3pcs height adjustable six-blade paddle
Stir speed: 50~1000rpm/50-400rpm

Sterilization

Sterilize in place(SIP), auto control by program

Clean

Clean in place (CIP) by spray ball

Gas control

Control by rotor meter, air flow 1 vvm

Feeding

Automatically feeding by peristaltic pump

Anti-foam control

Automatically add antifoam by peristaltic pump

Temperature control

Auto-control, electric heating range: water source add 5℃ to 70℃

PH control

PH 2.00-12.00±0.1, auto-control adding acid/base by peristaltic pump, pH sensor from Hamilton/Mettler, Switzerland.

Do control

0-150±3% displaying precision 0.1%, DO sensor from Hamilton/Mettler, Switzerland. DO coupling with agitation, oxygen.

Sampling

Sampling valve, can sterilization separately, manual

Harvest

Zero dead zone bottom valve(Gemu/Burket, Germany), can sterilization separately, manual/auto

Lid lift system

30L-500L have lid lift system, 700-1000L have human hole.

Pressure

Auto control, BD Germany pressure transmitter

Exhaust

Have condenser before exhaust, control by diagram valve / Proportional control valve.

Control parameters

10 or 15 inch touch screen, Siemens PLC with control parameters (stirring, pH, DO, temperature, feeding, alarm, gas etc.), data analysis, data record, data output, language(RU/EN/CN) and other customized functions

Optional configuration

Remote control, Mass flow meter(auto control gas), O2/N2/CO2, gas flow 2vvm, gas(CO2) exhaust analysis, Level sensor,  Turbidity(OD) sensor, ORP sensor, Weight system, Live cell sensor(Biomass), Printing, Siemens touch screen, Double mechanical seal, 4-Valves-group for feeding, Bottom valve auto discharge, ASME certificate, CSA certificate, Batch culture, Seed transfer, etc.

 

features

Why Leading Pharma Companies Specify Our ​Plant Cell Bioreactor​

• ​​Secondary Metabolite Optimization​​ – Specialized impellers reduce shear stress
• ​​Scale-Up Ready​​ – Identical geometry from 5L to 200KL
• ​​Critical Process Controls:​​

- Programmable metabolite feeding strategies

- Photoperiod simulation (optional)

- Redundant sterility safeguards

 

Product Structure

 

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The construction of a plant cell bioreactor involves many aspects, including but not limited to tank design, internal structure, stirring system, ventilation system and control system, which together ensure the effective fermentation process and the guarantee of product quality.

Product application

Ideal Applications​​

• ​​Taxol Production​​ – Taxus cell line cultivation
• ​​Rare Ginsenosides​​ – Panax cell culture systems
• ​​Plant-Based Vaccines​​ – Transgenic root cultures
• ​​Vanillin Biosynthesis​​ – Vanilla planifolia cell lines

 

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