Pharmaceutical Bioreactor
Pharmaceutical Bioreactor

Pharmaceutical Bioreactor

Pharmaceutical bioreactor is a specialized equipment for cell culture session, mainly used in biopharmaceutical research and development and production in order to produce antigens, antibodies and other products, but also involves the screening of strains and cell lines and process optimization, especially in response to sudden infectious diseases.
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Pharmaceutical Bioreactor Description

 

Pharmaceutical bioreactor is a specialized equipment for cell culture session. Products are displayed as follows:

Bioreactor

 

Pharmaceutical Bioreactor Work principle

 

Pharmaceutical bioreactors work on the following principles:

  • Firstly, bioreactors allow for continuous culture with stable quality and measurement of feed flow;
  • Secondly, bioreactors are used to culture cells in order to produce products such as antigens and antibodies, which support the large-scale production of biologics;
  • Lastly, cells or microorganisms are cultured in bioreactors in order to produce the required drugs, vaccines and other biologically active substances.

 

Pharmaceutical Bioreactor Specification

 

Speed control

Intelligent automatic PID control, pulse width modulation rare earth DC motor + gearbox, stirring speed: 50-1000rpm, variable speed, accuracy ± 5 ‰

DO control

PID intelligent automatic control, imported Swiss electrodes and cables, measuring range: 0-150%, control accuracy: ± 3%. Resolution 0.1%, according to the fermentation process controlled by fermentation time sequence(DO automatic variable control, multi-segment), can associated control with speed, air flow, pressure, feeding and other parameters

PH control

Intelligent PID automatic control, imported Swiss electrodes and cables, two peristaltic pumps.

Display range: 0.00 to 14.00 ± 0.01, control range: 2.00 to 12.00 ± 0.02.

Online detection, automatic alarm, automatically add acid/alkali solution by peristaltic pump

pH value curve analysis, acid/alkali volume curve analysis, quantitative analysis batch report,

The cumulative amount of acid/alkali added display records,

Control the fermentation process by fermentation time sequence

(pH automatic variable controller, multi-segment)

Temperature control

Intelligent PID automatic control, thermostatic bath + PT100 temperature sensor + electric heating + solenoid valve range; cooling water temperature +3 -60 ℃, accuracy of ± 0.2 ℃, 0.1 ℃ resolution

Feeding control

Air ratio control switch can be set to 1-100%, automatic flow and measured.

Supplement feeding amount curve analysis, the amount accumulated, display records, save of batch reports analyze.

Control the fermentation process segment by fermentation time sequence(automatic feeding variables, multi-segment) .

Dedicated pins and needles feeding sets, to ensure safe operation of feeding.

Defoaming control

Intelligent PID automatic control, electrode detection, adding defoamer by

peristaltic pump, sensitivity 100-100000Ω, can supplement quantitative and timing.

Ventilation

Manual adjustment, the flow meter measure, ventilation 1: 1-2VVM

Pressure

Manual adjustment, pressure gauge measure, the range 0-0.2MPa

Sterilization

Manual adjustment, the program assisted sterilization, sterilization reign / off-site.

 

Technical parameters

 

  • Temperature adjustment setting
  • Automatic feeding and replenishing function

 

Pharmaceutical Bioreactor highlights

 

  • Culture medium sterilizing type
  • Reducer motor
  • Process piping

 

Bioreactor

 

Pharmaceutical Bioreactor advantages

 

  • Data visualization and parameterization
  • Space-saving laboratory, small footprint
  • Reduced manual intervention, improved data repeatability and accuracy

 

Application

 

  • Cell culture
  • Vaccine development and many other applications
  • Food fermentation

 

Pharmaceutical Bioreactor

 

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